I was watching the Big Bang Theory DVDs and a thought occured to me.   While everyone loves Penny and Bernadette, think about this:

Rajesh' mom and sister!  Mrs and Priya Koothrappali.  Everyone thinks Raj can't talk in front of women because his father pushed him to be a Gynecologist.  But maybe it's because Mama and Big Sister Koothrappali laid claim to Raj's sex life...